SCP-1280 — SCP-1280 | Cost Breakdown

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SCP-1280 Euclid ~ medium confidence

SCP-1280

Expected annual

$2.8M

One-time setup

$1.4M

Annual recurring

$2.8M

Personnel

Initial capital costs are approximately $1.40M driven by lab fit-out, contingency reserve, and secure infrastructure; ongoing annual operations are approximately $2.60M driven by personnel, advanced research, security, surveillance, and field response readiness.

🏗️ One-Time Capital Costs Total: $1.4M

Contingency Reserve $500K

[#22] One-time contingency/emergency response reserve fund (set-aside for rapid remediation, mass treatment, quarantines, PR/cover-up).

Facilities $350K

[#1] BSL-2 laboratory fit-out: negative-pressure ventilation adjustments, cleanable surfaces, secure access control, chemical-resistant benching, dedicated climate control/incubators.

Equipment $150K

[#2] Essential laboratory equipment: microscopes, refrigerated centrifuge, PCR thermocycler, -80°C freezer, spectrophotometer, cryo-storage, cold-chain fridges.

Community Rehab Reserve $100K

[#27] One-time reserve for small-community rehabilitation programs / institutional replacement.

Database Setup $60K

[#15] Long-term epidemiological monitoring database setup and secure server deployment.

Mobile Field Lab Purchase $50K

[#13] Mobile field lab & diagnostics kit purchase (portable PCR, microscopes, centrifuges).

Hygiene Infrastructure Construction $50K

[#10] Seed construction fund for sealed latrines / immediate WASH interventions for a small settlement.

Initial Research And Lab Setup $30K

[#3] Initial reagent and consumables stock for setup: culture media, Petri dishes, pipette tips, stains, extraction kits, sequencing library kits (initial stock).

Cctv And Security Hardware $30K

[#21] CCTV, alarms and on-site physical security hardware purchase.

Cover Organization Setup $30K

[#23] Cover NGO shell legal registration, branding, initial office setup.

Community Campaign Initial $20K

[#11] Initial community health education campaign design and delivery costs.

Drone Purchase $20K

[#25] Purchase of drone reconnaissance equipment for surveillance/investigation.

Ppe Training $6K

[#7] Initial biosafety training and fit-testing one-time costs.

🔄 Annual Recurring Costs Total: $2.8M/yr

Staff Wages $450K/yr

[#5] Salaries and benefits for research team (1 PI, ~2 senior researchers, ~2 lab technicians, 1 lab manager).

Research And Monitoring $400K/yr

[#16] Advanced research program ongoing costs (genomics, transcriptomics, mechanism studies, animal-model experiments over multi-year program).

Security Guards And Monitoring $332K/yr

[#21] Salaries and benefits for 6 on-site guards or equivalent contracted security plus monitoring fees.

Animal Vivarium Ops $300K/yr

[#17] Animal model maintenance, husbandry and behavioral testing suites for in vivo studies.

Cover Story And Legal $150K/yr

[#23, #26] Annual cover NGO operating budget and legal/ethical/regulatory retainers.

Soil Surveillance $150K/yr

[#14] Regional environmental surveillance program for soil sampling, larval assays, qPCR and hotspot mapping.

Epidemiology Staff $150K/yr

[#15] Ongoing epidemiologists and field data collectors to manage database and case follow-up.

Logistics And Transport $100K/yr

[#12] Field deployment readiness fund for travel, vehicles, per diem and short deployments (MTF-style interventions).

Cover Organization Ops $100K/yr

[#23] Annual operating budget for the cover humanitarian organization presence in-region.

Redundancy Reserve $100K/yr

[#30] Budget for redundancy/mirroring essential capabilities at alternate sites due to restricted collaboration.

Ongoing Culture Maintenance $75K/yr

[#4] Weekly inspections, feeding, media changes, viability checks and waste handling for multiple active culture lines (estimated 3 lines).

Facilities Maintenance $60K/yr

[#28] Utilities and facilities overhead (electricity, HVAC for incubators/freezers, rent amortization, general maintenance).

Amnestic And Counseling $50K/yr

[#18] Counseling services and conservative budget for amnestic administration support per year.

Contingency Topups $50K/yr

[#22] Annual top-ups to emergency remediation contingency/reserve.

Legal Retainer $50K/yr

[#26] Legal, ethical and regulatory counsel retainers and per-case fees.

Community Rehab Program $50K/yr

[#27] Ongoing small-community rehabilitation program costs (psychosocial support, school/economic support).

Sample Screening $30K/yr

[#6] Weekly PCR-based stool screening for staff (5 staff, PCR preferred for sensitivity).

Community Health Workers $30K/yr

[#11] Salaries for ongoing community health worker(s) executing education and follow-up.

Biohazard Waste Disposal $20K/yr

[#20] Contract disposal, autoclave operation and incineration budget based on throughput.

Public Relations $20K/yr

[#24] PR, liaison, translations and local government cooperation budgets.

Aircraft Drone Surveillance $20K/yr

[#25] Recurring budget for radar/satellite data purchases, drone ops and occasional chartering for aerosolization investigations.

Training And Drills $20K/yr

[#29] Regular biosafety, outbreak response and MDA drills and training.

Supplies And Consumables $10K/yr

[#3] Reagent and consumable baseline resupply (media, tips, reagents) estimated lower-bound annual replenishment.

Reagent Resupply $10K/yr

[#3] Recurring portion of initial reagent/consumables resupply (alternate placement for audit mapping).

Ppe Consumables $10K/yr

[#7] Ongoing PPE replacement and consumables; excludes one-time training.

Hygiene Maintenance $10K/yr

[#10] Maintenance and hygiene program follow-up for latrines and WASH infrastructure.

Mda Readiness Fund $5K/yr

[#9] Baseline preparedness for antelmintic MDA logistics (stockpile/rapid procurement readiness).

Mobile Field Lab Consumables $5K/yr

[#13] Operational consumables for mobile diagnostics per-deployment baseline.

Specimen Transport $5K/yr

[#19] Secure IATA-compliant shipments, cold-chain couriers and permit renewals baseline.

Medical Stock $500/yr

[#8] Annual restocking of emergency albendazole courses for lab staff.

⚡ Cost Scenarios

📊 Baseline (baseline) $2.8M/yr

87.0% probability / year

Normal year with routine operations, surveillance, and readiness, no major outbreak or large-scale response.

no outbreak routine surveillance scheduled research activities

🚨 Minor Incident $2.8M/yr

10.0% probability / year +$70K vs baseline

Single small settlement outbreak requiring localized MDA, hygiene interventions, targeted field deployment and local counseling.

detection of localized community infestation single-campaign MDA small field deployment

🚨 Major Breach $4.1M/yr

2.0% probability / year +$1.3M vs baseline

Containment breach or lab-acquired spread causing multi-village transmission requiring large-scale MDA, emergency remediation, major PR/legal action and significant use of contingency funds.

lab-acquired infection with community spread multi-village MDA requirement large emergency response

🚨 Aerosolized Investigation $3.1M/yr

1.0% probability / year +$340K vs baseline

Investigation into suspected aerosolized deployment (crop-duster), requiring chartered aircraft, broad surveillance and expanded field response.

evidence of aerosol dissemination need for extensive forensic air sampling regional surveillance expansion

👥 Personnel 20 total

Role	Count	Notes
Principal Investigator	1	[#5] Senior research leadership included in staff_wages.
Research Scientist / Senior Researcher	2	[#5, #16] Experimental and genomics staff funded in research program and staff_wages.
Lab Technician	2	[#5] Lab technicians for culture maintenance and assays.
Lab Manager	1	[#5] Operational oversight and biosafety compliance.
Security Officer / Guard	6	[#21] On-site security staffing to prevent unauthorized access and theft.
Epidemiologist	1	[#15] Lead epidemiologist managing database and regional surveillance.
Field Data Collector	2	[#15, #14] Field surveillance and sample collection staff.
Community Health Worker	1	[#11] Ongoing community education and follow-up.
Administrative Staff	2	[#23] Cover organization and administrative support.
Veterinary / Animal Care Technician	2	[#17] Vivarium and animal model husbandry staff.

📋 Confidence Notes

Analyst notes provide detailed line-item ranges enabling mid-range estimates, but many items (outbreak scale, frequency, research scope, amnestic costs, aerosolization investigations) are highly variable; therefore confidence is medium.

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