[#1, #4, #10, #12, #14, #24] BSL-4 construction/retrofit, HVAC/atmosphere system installation, OR retrofit and containment-capable quarantine center setup, incinerator installation, and containment logistics hub setup. Estimate assumes one central BSL-4 site, a small set of regional quarantine rooms, and associated structural installations.

[#22] One-time seed for emergency outbreak contingency reserve (operational reserve to enable surge capacity).

[#5, #8, #18, #23] Environmental sensor networks and integration, initial epidemiological data platform build, initial R&D scale-up and lab buildout (sequencers/qPCR/breathalyzer dev), and startup reagent/instrument validation costs.

[#2, #3, #9, #11, #15] Purchase of Class III biosafety cabinets (multiple units), initial positive-pressure suit inventory, one field biocontainment ambulance/flight module, cryoablation unit and specialized surgical instruments, and a high-capacity autoclave.

[#8, #10, #12, #18, #26] Salaries and benefits for research staff (PIs/postdocs/techs), epidemiologists/data analysts, thoracic surgical and ICU teams, quarantine-care staffing, embedded public-health liaisons and administrative/security staff. Headcount breakdown is provided in personnel.

[#5, #7, #8, #18, #23, #28] Ongoing environmental/clinical monitoring (air samplers, PCR processing), routine clinical testing and imaging programs, data platform licensing/maintenance, and core R&D program funding for treatment/eradication research and surveillance (regional environmental surveillance).

[#22] Annual replenishment/contribution to the contingency reserve to maintain surge funding capability after draws for response actions.

[#6, #11, #15, #16, #23] Ongoing prophylactic pill procurement/distribution, surgical/disposable consumables for contained procedures, chemical sterilants, autoclave consumables, PPE consumables (gloves, filters, disinfectants), and diagnostics consumables.

[#12, #20, #26] Ongoing legal, PR, front-corporation operations (Sympathetic Care Providers), cover-story maintenance, liaison/grant payments and selective influence operations to preserve secrecy and operate quarantine housing fronts.

[#13, #21] Production/acquisition of amnestic agents, medical administration sessions, psychiatric follow-up, record alteration/expungement and per-case amnestic costs (program overhead plus case treatments).

[#17] Regular BSL-4 training, suit pressurization/fitting/testing, emergency response drills, surgical practice under containment and certification programs for high-risk staff.

[#30] Ongoing contingency planning, scenario exercises, and maintained contracts for large-scale mitigation planning (does not include full-scale response costs).

[#19] Multi-month/annual clinical follow-up and monitoring for released subjects, imaging and laboratory testing for recurrence, and contact tracing resources.

[#9, #24, #27] Vehicle/ambulance operating costs, courier and secure sample transport network operations, med-evac/transport insurance and temperature-controlled shipment logistics.

[#4, #5, #14, #15, #25] HVAC/atmospheric regulation maintenance and calibration, continuous environmental sensor servicing, incinerator servicing, autoclave servicing/validation, HEPA filter replacement and energy/utility costs for sealed BSL-4 operations.

[#26] Embedded personnel, grants, and small-to-medium payments to maintain cooperative relationships with public health agencies and hospitals for quiet reporting and early detection.

[#29] Counseling, reintegration allowances, stipends, temporary housing and hush payments implemented for quarantined/released subjects to ensure cooperation and mitigate leaks.